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10-Formyl-5,8-dideazafolic acid
CAS No. 61038-31-1
10-Formyl-5,8-dideazafolic acid( —— )
Catalog No. M35686 CAS No. 61038-31-1
10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Name10-Formyl-5,8-dideazafolic acid
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NoteResearch use only, not for human use.
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Brief Description10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate.
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Description10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number61038-31-1
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Formula Weight467.43
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Molecular FormulaC22H21N5O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (106.97 mM; Ultrasonic )
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SMILESNc1nc(=O)c2cc(CN(C=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)ccc2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.
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