10-Formyl-5,8-dideazafolic acid

CAS No. 61038-31-1

10-Formyl-5,8-dideazafolic acid( —— )

Catalog No. M35686 CAS No. 61038-31-1

10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    10-Formyl-5,8-dideazafolic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate.
  • Description
    10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    61038-31-1
  • Formula Weight
    467.43
  • Molecular Formula
    C22H21N5O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (106.97 mM; Ultrasonic )
  • SMILES
    Nc1nc(=O)c2cc(CN(C=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)ccc2[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.
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